Correcting for batch effects in case-control microbiome studies.

High-throughput data generation platforms, like mass-spectrometry, microarrays, and second-generation sequencing are susceptible to batch effects due to run-to-run variation in reagents, equipment, protocols, or personnel. Currently, batch correction methods are not commonly applied to microbiome se...

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Bibliographic Details
Main Authors: Sean M Gibbons, Claire Duvallet, Eric J Alm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5940237?pdf=render