Avenanthramide C Suppresses Matrix Metalloproteinase-9 Expression and Migration Through the MAPK/NF- κB Signaling Pathway in TNF-α-Activated HASMC Cells

Avenanthramide C Suppresses Matrix Metalloproteinase-9 Expression and Migration Through the MAPK/NF- κB Signaling Pathway in TNF-α-Activated HASMC Cells

In oat ingredients, flavonoids and phenolic acids are known to be the most important phenolic compounds. In phenolic compounds, wide-ranging biological responses, including antioxidative, anti-inflammatory, anti-allergic, and anti-cancer properties, were reported. Avenanthramide C (Avn C), a compone...

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Bibliographic Details
Main Authors: Junyoung Park, Hyunju Choi, Fukushi Abekura, Hak‐Seong Lim, Jong‐Hwan Im, Woong‐Suk Yang, Cher‐Won Hwang, Young‐Chae Chang, Young-Choon Lee, Nam Gyu Park, Cheorl-Ho Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
anti-atherosclerosis
MMP
TNF-α
HASMCs (human aortic smooth muscle cells)
avenanthramide C
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.621854/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.621854/full

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