Akkermansia Muciniphila Potentiates the Antitumor Efficacy of FOLFOX in Colon Cancer

Akkermansia Muciniphila Potentiates the Antitumor Efficacy of FOLFOX in Colon Cancer

FOLFOX (oxaliplatin, fluorouracil and calcium folinate) is the first-line chemotherapy regimen for colon cancer therapy in the clinic. It provides superior efficacy than oxaliplatin alone, but the underlying mechanism remains unclear. In the present study, pharmacomicrobiomics integrated with metabo...

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Bibliographic Details
Main Authors: Xiaoying Hou, Pei Zhang, Hongzhi Du, Weihua Chu, Ruiqi Sun, Siyuan Qin, Yuan Tian, Zunjian Zhang, Fengguo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
FOLFOX
oxaliplatin
colon cancer
Akkermansia muciniphila
pharmacomicrobiomics
metabolomics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.725583/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.725583/full

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