Combination Therapy of Mesenchymal Stromal Cells and Interleukin-4 Attenuates Rheumatoid Arthritis in a Collagen-Induced Murine Model

Combination Therapy of Mesenchymal Stromal Cells and Interleukin-4 Attenuates Rheumatoid Arthritis in a Collagen-Induced Murine Model

Rheumatoid arthritis (RA) is a disease of the joints that causes decreased quality of life. Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with possible use in the treatment of RA. Similarly, interleukin (IL)-4 has been shown as a potential RA treatment. However, their combinati...

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Bibliographic Details
Main Authors: Shaimaa M. Haikal, Nourtan F. Abdeltawab, Laila A. Rashed, Tarek I. Abd El-Galil, Heba A. Elmalt, Magdy A. Amin
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
rheumatoid arthritis
auto-inflammatory disease
cytokines
IL-4
mesenchymal stem cells
mouse model
collagen-induced arthritis
inflammatory mediators
Online Access:https://www.mdpi.com/2073-4409/8/8/823

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https://www.mdpi.com/2073-4409/8/8/823

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