Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism

Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism

Alcohol-induced progression of hepatitis C virus (HCV) infection is related to dysfunction of innate immunity in hepatocytes. Endogenously produced interferon (IFN)α induces activation of interferon-stimulated genes (ISGs) via triggering of the Janus kinase–signal transducer and activator of transcr...

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Bibliographic Details
Main Authors: Murali Ganesan, Irina Tikhanovich, Shiva Shankar Vangimalla, Raghubendra Singh Dagur, Weimin Wang, Larisa I. Poluektova, Yimin Sun, David F. Mercer, Dean Tuma, Steven A. Weinman, Kusum K. Kharbanda, Natalia A. Osna
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Alcohol
HCV
JMJD6
STAT1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X17301509

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http://www.sciencedirect.com/science/article/pii/S2352345X17301509

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