Preparation and characterization of a novel nanobody against T-cell immunoglobulin and mucin-3 (TIM-3)

Objective(s): As T-cell immunoglobulin and mucin domain 3 (TIM-3) is an immune regulatory molecule; its blocking or stimulating could alter the pattern of immune response towards a desired condition. Based on the unique features of nanobodies, we aimed to construct an anti-TIM-3 nanobody as an appro...

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Bibliographic Details
Main Authors: Vida Homayouni, Mazdak Ganjalikhani-hakemi, Abbas Rezaei, Hossein Khanahmad, Mahdi Behdani, Fatemeh Kazemi Lomedasht
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_7820_62b85dc2cb571a9f88fd37dc253dffa0.pdf