Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala

Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala

Abstract Background Maternal immune activation (MIA) is a risk factor for neurodevelopmental disorders such as autism and schizophrenia, as well as seizure development. The amygdala is a brain region involved in the regulation of emotions, and amygdalar maldevelopment due to infection-induced MIA ma...

Full description

Bibliographic Details
Main Authors: Elaine O’Loughlin, Janelle M. P. Pakan, Deniz Yilmazer-Hanke, Kieran W. McDermott
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Neuroinflammation
Subjects:
Maternal inflammation
Amygdala
Neuroinflammation
Neurodevelopment
Amygdalar development
Inflammatory cytokines
Online Access:http://link.springer.com/article/10.1186/s12974-017-0981-8

Internet

http://link.springer.com/article/10.1186/s12974-017-0981-8

Similar Items