Inducing and administering Tregs to treat human disease

Regulatory T cells control unwanted immune responses including those that mediate tolerance to self as well as to foreign antigens. Their mechanisms of action include direct and indirect effects on effector T cells and important functions in tissue repair and homeostasis. Regulatory T cells express...

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Bibliographic Details
Main Authors: Ana Luisa Perdigoto, Lucienne eChatenoud, Jeffrey A Bluestone, Kevan C Herold
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00654/full