Is age‐related increase of chromosome segregation errors in mammalian oocytes caused by cohesin deterioration?
Abstract Background Mammalian oocytes initiate meiosis in fetal ovary and are arrested at dictyate stage in prophase I for a long period. It is known that incidence of chromosome segregation errors in oocytes increases with advancing age, but the molecular mechanism underlying this phenomenon has no...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Reproductive Medicine and Biology |
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| Online Access: | https://doi.org/10.1002/rmb2.12299 |