Lnc-STYK1-2 regulates bladder cancer cell proliferation, migration, and invasion by targeting miR-146b-5p expression and AKT/STAT3/NF-kB signaling

Lnc-STYK1-2 regulates bladder cancer cell proliferation, migration, and invasion by targeting miR-146b-5p expression and AKT/STAT3/NF-kB signaling

Abstract Background Epigenetic modulation by noncoding RNAs substantially contributes to human cancer development, but noncoding RNAs involvement in bladder cancer remains poorly understood. This study investigated the role of long noncoding RNA (lncRNA) lnc-STYK1-2 in tumorigenesis in cancerous bla...

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Bibliographic Details
Main Authors: Ranran Dai, Qingping Jiang, You Zhou, Ruifeng Lin, Hai Lin, Yumin Zhang, Jinhu Zhang, Xingcheng Gao
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cancer Cell International
Subjects:
Lnc-STYK1-2
Bladder cancer
miR-146b-5p
Proliferation
Migration and invasion
ITGA2
Online Access:https://doi.org/10.1186/s12935-021-02114-4

Internet

https://doi.org/10.1186/s12935-021-02114-4

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