Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity

Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity

Despite extensive scrutiny of the myosin superfamily, the lack of high-resolution structures of actin-bound states has prevented a complete description of its mechanochemical cycle and limited insight into how sequence and structural diversification of the motor domain gives rise to specialized func...

Full description

Bibliographic Details
Main Authors: Pinar S Gurel, Laura Y Kim, Paul V Ruijgrok, Tosan Omabegho, Zev Bryant, Gregory M Alushin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
molecular motors
cytoskeleton
myosin
actin
Cryo-EM
Online Access:https://elifesciences.org/articles/31125

Internet

https://elifesciences.org/articles/31125

Similar Items