Polymer-Mediated Delivery of siRNAs to Hepatocellular Carcinoma: Variables Affecting Specificity and Effectiveness

Polymer-Mediated Delivery of siRNAs to Hepatocellular Carcinoma: Variables Affecting Specificity and Effectiveness

Despite the advances in anticancer therapies, their effectiveness for many human tumors is still far from being optimal. Significant improvements in treatment efficacy can come from the enhancement of drug specificity. This goal may be achieved by combining the use of therapeutic molecules with tumo...

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Bibliographic Details
Main Authors: Rossella Farra, Francesco Musiani, Francesca Perrone, Maja Čemažar, Urška Kamenšek, Federica Tonon, Michela Abrami, Aleš Ručigaj, Mario Grassi, Gabriele Pozzato, Deborah Bonazza, Fabrizio Zanconati, Giancarlo Forte, Maguie El Boustani, Lucia Scarabel, Marica Garziera, Concetta Russo Spena, Lucia De Stefano, Barbara Salis, Giuseppe Toffoli, Flavio Rizzolio, Gabriele Grassi, Barbara Dapas
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
optimized drug delivery
siRNA
HCC
Online Access:http://www.mdpi.com/1420-3049/23/4/777

Internet

http://www.mdpi.com/1420-3049/23/4/777

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