Genome-Wide DNA Copy Number Analysis of Acute Lymphoblastic Leukemia Identifies New Genetic Markers Associated with Clinical Outcome.

UNLABELLED:Identifying additional genetic alterations associated with poor prognosis in acute lymphoblastic leukemia (ALL) is still a challenge. AIMS:To characterize the presence of additional DNA copy number alterations (CNAs) in children and adults with ALL by whole-genome oligonucleotide array (a...

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Main Authors: Maribel Forero-Castro, Cristina Robledo, Rocío Benito, María Abáigar, Ana África Martín, Maryam Arefi, José Luis Fuster, Natalia de Las Heras, Juan N Rodríguez, Jonathan Quintero, Susana Riesco, Lourdes Hermosín, Ignacio de la Fuente, Isabel Recio, Jordi Ribera, Jorge Labrador, José M Alonso, Carmen Olivier, Magdalena Sierra, Marta Megido, Luis A Corchete-Sánchez, Juana Ciudad Pizarro, Juan Luis García, José M Ribera, Jesús M Hernández-Rivas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4752220?pdf=render