A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells.

MicroRNAs (miRNAs) post-transcriptionally regulate the expression of thousands of distinct mRNAs. While some regulatory interactions help to maintain basal cellular functions, others are likely relevant in more specific settings, such as response to stress. Here we describe such a role for the mir-2...

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Bibliographic Details
Main Authors: Grace X Y Zheng, Arvind Ravi, J Mauro Calabrese, Lea A Medeiros, Oktay Kirak, Lucas M Dennis, Rudolf Jaenisch, Christopher B Burge, Phillip A Sharp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3088722?pdf=render