Peptide Dose and/or Structure in Vaccines as a Determinant of T Cell Responses

While T cells recognise the complex of peptide and major histocompatibility complex (MHC) at the cell surface, changes in the dose and/or structure of the peptide component can have profound effects on T cell activation and function. In addition, the repertoire of T cells capable of responding to an...

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Bibliographic Details
Main Author: Graham R. Leggatt
Format: Article
Language:English
Published: MDPI AG 2014-07-01
Series:Vaccines
Subjects:
Online Access:http://www.mdpi.com/2076-393X/2/3/537