Introducing a new estimator and test for the weighted all-cause hazard ratio

Introducing a new estimator and test for the weighted all-cause hazard ratio

Abstract Background The rationale for the use of composite time-to-event endpoints is to increase the number of expected events and thereby the power by combining several event types of clinical interest. The all-cause hazard ratio is the standard effect measure for composite endpoints where the all...

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Bibliographic Details
Main Authors: Ann-Kathrin Ozga, Geraldine Rauch
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Medical Research Methodology
Subjects:
Composite endpoint
Weighted effect measure
Weight-based log-rank test
Simulation study
Online Access:http://link.springer.com/article/10.1186/s12874-019-0765-1

Internet

http://link.springer.com/article/10.1186/s12874-019-0765-1

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