Synthesis, Crystal Structure, and Solubility Analysis of a Famotidine Cocrystal

A novel cocrystal of the potent H<sub>2</sub> receptor antagonist famotidine (FMT) was synthesized with malonic acid (MAL) to enhance its solubility. The cocrystal structure was characterized by X-ray single crystal diffraction, and the asymmetry unit contains one FMT and one MAL connect...

Full description

Bibliographic Details
Main Authors: Yan Zhang, Zhao Yang, Shuaihua Zhang, Xingtong Zhou
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/9/7/360