NF-κB activation triggers NK-cell stimulation by monocyte-derived dendritic cells

Background: In therapeutic cancer vaccination, monocyte-derived dendritic cells (moDCs) efficiently activate specific T-cell responses; however, optimizing the activation of innate immune cells could support and improve the antitumor effects. A major disadvantage of moDCs matured with the standard c...

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Bibliographic Details
Main Authors: Naomi C. Bosch, Reinhard E. Voll, Caroline J. Voskens, Stefanie Gross, Barbara Seliger, Gerold Schuler, Niels Schaft, Jan Dörrie
Format: Article
Language:English
Published: SAGE Publishing 2019-12-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758835919891622