Molecular docking study on the potency of glycosaminoglycans (GaGs) as co-activators of fibroblasts proliferation and differentiation

Fibroblast growth factors (FGF) are heparin-binding polypeptides that control differentiation, growth and migration of many cell types. The signaling in the FGF pathway implies the dimerization of their corresponding cell surface receptors and consequently their activation through autophosphorylatio...

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Bibliographic Details
Main Authors: Andrei Neamtu, Monica Neamtu, Tudor Petreus, Ana-Maria Oprea, Ostin Mungiu
Format: Article
Language:English
Published: "Alexandru Ioan Cuza" University of Iași 2010-01-01
Series:Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
Online Access:http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/737