Endothelial glycocalyx degradation and disease severity in Plasmodium vivax and Plasmodium knowlesi malaria

Abstract Degradation of the endothelial glycocalyx is associated with mortality in adult falciparum malaria. However, its role in the pathogenesis of non-falciparum malaria is unknown. In Malaysian patients with knowlesi (n = 200) and vivax (n = 61) malaria, and in healthy controls (n = 50), we meas...

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Bibliographic Details
Main Authors: Bridget E. Barber, Matthew J. Grigg, Kim A. Piera, Youwei Chen, Timothy William, J. Brice Weinberg, Tsin W. Yeo, Nicholas M. Anstey
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88962-6