Regulation of opioid receptor signalling: Implications for the development of analgesic tolerance

<p>Abstract</p> <p>Opiate drugs are the most effective analgesics available but their clinical use is restricted by severe side effects. Some of these undesired actions appear after repeated administration and are related to adaptive changes directed at counteracting the consequenc...

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Bibliographic Details
Main Authors: Nagi Karim, Piñeyro Graciela
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/4/1/25