Molecular Control of Follicular Helper T cell Development and Differentiation

Molecular Control of Follicular Helper T cell Development and Differentiation

Follicular helper T cells (Tfh) are specialized helper T cells that are predominantly located in germinal centers and provide help to B cells. The development and differentiation of Tfh cells has been shown to be regulated by transcription factors, such as B-cell lymphoma 6 protein (Bcl-6), signal t...

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Bibliographic Details
Main Authors: Haijing Wu, Yaxiong Deng, Ming Zhao, Jianzhong Zhang, Min Zheng, Genghui Chen, Linfeng Li, Zhibiao He, Qianjin Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Tfh
Bcl-6
Blimp-1
transcription factors
epigenetics
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02470/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02470/full

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