Chronic ketamine impairs fear conditioning and produces long-lasting reductions in auditory evoked potentials

Chronic ketamine impairs fear conditioning and produces long-lasting reductions in auditory evoked potentials

Ketamine is an NMDA receptor antagonist with a variety of uses, ranging from recreational drug to pediatric anesthetic and chronic pain reliever. Despite its value in the clinical setting, little is known about the immediate and long-lasting effects of repeated ketamine treatment. We assessed the ef...

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Bibliographic Details
Main Authors: Laura C. Amann, Tobias B. Halene, Richard S. Ehrlichman, Stephen N. Luminais, Nan Ma, Ted Abel, Steven J. Siegel
Format: Article
Language:English
Published: Elsevier 2009-08-01
Series:Neurobiology of Disease
Subjects:
Ketamine
Event-related potential (ERP)
Auditory evoked potential (AEP)
Gating
Fear conditioning
Schizophrenia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109001132

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http://www.sciencedirect.com/science/article/pii/S0969996109001132

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