Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer.

Inflammatory bowel disease (IBD) is a disorder of chronic inflammation with increased susceptibility to colorectal cancer. The etiology of IBD is unclear but thought to result from a dysregulated adaptive and innate immune response to microbial products in a genetically susceptible host. Toll-like r...

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Bibliographic Details
Main Authors: Emily L Lowe, Timothy R Crother, Shervin Rabizadeh, Bing Hu, Hanlin Wang, Shuang Chen, Kenichi Shimada, Michelle H Wong, Kathrin S Michelsen, Moshe Arditi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2946405?pdf=render