VEGFC/VEGFR3 axis mediates TGFβ1-induced epithelial-to-mesenchymal transition in non-small cell lung cancer cells.

VEGFC/VEGFR3 axis mediates TGFβ1-induced epithelial-to-mesenchymal transition in non-small cell lung cancer cells.

In the tumor progression, transforming growth factor β1 (TGFβ1) plays a critical role in tumorigenesis as well as metastasis. It is known that high plasma level of TGFβ1 in patients with advanced non-small cell lung cancer (NSCLC) is correlated with poor prognostics. In addition, the generation of c...

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Bibliographic Details
Main Authors: Lincan Duan, Lianhua Ye, Li Zhuang, Xiaolan Zou, Shan Liu, Yong Zhang, Lijuan Zhang, Congguo Jin, Yunchao Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6040758?pdf=render

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http://europepmc.org/articles/PMC6040758?pdf=render

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