Neuroprotective Effects and Mechanisms of Curcumin–Cu(II) and –Zn(II) Complexes Systems and Their Pharmacological Implications

Alzheimer’s disease (AD) is the main form of dementia and has a steadily increasing prevalence. As both oxidative stress and metal homeostasis are involved in the pathogenesis of AD, it would be interesting to develop a dual function agent, targeting the two factors. Curcumin, a natural compound iso...

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Bibliographic Details
Main Authors: Fa-Shun Yan, Jian-Long Sun, Wen-Hai Xie, Liang Shen, Hong-Fang Ji
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/10/1/28