Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

<p>Abstract</p> <p>Histone deacetylases (HDACs) can regulate expression of tumor suppressor genes and activities of transcriptional factors involved in both cancer initiation and progression through alteration of either DNA or the structural components of chromatin. Recently, the r...

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Bibliographic Details
Main Authors: Petrillo Richard L, Ma Yuehua, Cang Shundong, Tan Jiahuai, Liu Delong
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/3/1/5