Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia‐Ischemia

Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia‐Ischemia

Preterm neonates are susceptible to perinatal hypoxic‐ischemic brain injury, for which no treatment is available. In a preclinical animal model of hypoxic‐ischemic brain injury in ovine fetuses, we have demonstrated the neuroprotective potential of systemically administered mesenchymal stromal cells...

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Bibliographic Details
Main Authors: Daan R.M.G. Ophelders, Tim G.A.M. Wolfs, Reint K. Jellema, Alex Zwanenburg, Peter Andriessen, Tammo Delhaas, Anna-Kristin Ludwig, Stefan Radtke, Vera Peters, Leon Janssen, Bernd Giebel, Boris W. Kramer
Format: Article
Language:English
Published: Wiley 2016-06-01
Series:Stem Cells Translational Medicine
Subjects:
Hypoxia-ischemia
Brain injury
Preterm
Mesenchymal stromal cells
Extracellular vesicles
Exosomes
Online Access:https://doi.org/10.5966/sctm.2015-0197

Internet

https://doi.org/10.5966/sctm.2015-0197

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