Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals

Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals

Abstract Background The tick-borne protozoan parasite Theileria parva causes a usually fatal cattle disease known as East Coast fever in sub-Saharan Africa, with devastating consequences for poor small-holder farmers. Immunity to T. parva, believed to be mediated by a cytotoxic T lymphocyte (CTL) re...

Full description

Bibliographic Details
Main Authors: Lucilla Steinaa, Nicholas Svitek, Elias Awino, Thomas Njoroge, Rosemary Saya, Ivan Morrison, Philip Toye
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Veterinary Research
Subjects:
Theileria parva
Live vaccine
Cytotoxic T cells
Immunity
Strain specificity
Online Access:http://link.springer.com/article/10.1186/s12917-018-1460-x

Internet

http://link.springer.com/article/10.1186/s12917-018-1460-x

Similar Items