Safety and Efficacy of Ketamine Versus Ketamine-Fentanyl-Dexmedetomidine Combination for Anesthesia and Analgesia in Rats

Ketamine (KET), a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, is most frequently used as an anesthetic, analgesic, and sedative drug in pediatric clinical practices. However, the adverse effects of KET administration such as psychotic episodes limited the use of KET. The aim of t...

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Bibliographic Details
Main Authors: Chunzhu Li, Jiali Peng, Rong Hu, Jia Yan, Yu Sun, Lei Zhang, Wenbin Liu, Hong Jiang
Format: Article
Language:English
Published: SAGE Publishing 2019-02-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325819825902