Enhanced oral delivery of insulin via the colon-targeted nanocomposite system of organoclay/glycol chitosan/Eudragit®S100

Enhanced oral delivery of insulin via the colon-targeted nanocomposite system of organoclay/glycol chitosan/Eudragit®S100

Abstract This study aimed to develop a ternary nanocomposite system of organoclay, glycol-chitosan, and Eudragit®S100 as an effective colon targeted drug delivery carrier to enhance the oral absorption of insulin. A nanocomplex of insulin and aminoclay was prepared via spontaneous co-assembly, which...

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Bibliographic Details
Main Authors: Sang Hoon Lee, Seung-Yun Back, Jae Geun Song, Hyo-Kyung Han
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Nanobiotechnology
Subjects:
Insulin
Oral delivery system
Colon targeting
Nano-carrier
Aminoclay
Online Access:http://link.springer.com/article/10.1186/s12951-020-00662-x

Internet

http://link.springer.com/article/10.1186/s12951-020-00662-x

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