Long Term Delta-9-tetrahydrocannabinol Administration Inhibits Proinflammatory Responses in Minor Salivary Glands of Chronically Simian Immunodeficieny Virus Infected Rhesus Macaques

Long Term Delta-9-tetrahydrocannabinol Administration Inhibits Proinflammatory Responses in Minor Salivary Glands of Chronically Simian Immunodeficieny Virus Infected Rhesus Macaques

HIV/SIV-associated oral mucosal disease/dysfunction (HAOMD) (gingivitis/periodontitis/salivary adenitis) represents a major comorbidity affecting HIV patients on anti-retroviral therapy. Using a systems biology approach, we investigated molecular changes (mRNA/microRNA) underlying HAOMD and its modu...

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Bibliographic Details
Main Authors: Xavier Alvarez, Karol Sestak, Siddappa N. Byrareddy, Mahesh Mohan
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
THC
HIV/SIV
rhesus macaque
minor salivary gland inflammation
miR-29b
Online Access:https://www.mdpi.com/1999-4915/12/7/713

Internet

https://www.mdpi.com/1999-4915/12/7/713

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