N-Methyl-N'-nitro-N-nitrosoguanidine-induced senescence-like growth arrest in colon cancer cells is associated with loss of adenomatous polyposis coli protein, microtubule organization, and telomeric DNA
<p>Abstract</p> <p>Background</p> <p>Cellular senescence is a state in which mammalian cells enter into an irreversible growth arrest and altered biological functions. The senescence response in mammalian cells can be elicited by DNA-damaging agents. In the present stud...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2004-01-01
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| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/3/1/3 |