FLT3 INTERNAL TANDEM DUPLICATION AND D835 MUTATIONS IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA AND ITS CLINICAL SIGNIFICANCE

The fms-like tyrosine kinase 3 (FLT3) gene is a member of the class III receptor tyrosine kinase family, mutations of FLT3 were first described in 1997 and account for the most frequent molecular mutations in acute myeloid leukemia. No data currently exist regarding FLT3 mutations in Saudi acute l...

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Bibliographic Details
Main Authors: Ghaleb Elyamany, Mohamed Awad, Omar Alsuhaibani, Kamal Fadalla, Omer Al Sharif, Mohammad Al Shahrani, Fahad Alabbas, Abdulaziz Al-Abulaaly
Format: Article
Language:English
Published: PAGEPress Publications 2014-05-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/1388