The dark side of insulin: A primary autoantigen and instrument of self-destruction in type 1 diabetes

Background: Since its discovery 100 years ago, insulin, as the ‘cure’ for type 1 diabetes, has rescued the lives of countless individuals. As the century unfolded and the autoimmune nature of type 1 diabetes was recognised, a darker side of insulin emerged. Autoimmunity to insulin was found to be an...

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Bibliographic Details
Main Author: Leonard C. Harrison
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001332