Signaling pathways involved in chronic myeloid leukemia pathogenesis: the importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells
Objective(s): Chronic myeloid leukemia (CML) is a myeloid clonal proliferation disease defining by the presence of the Philadelphia chromosome that shows the movement of BCR-ABL1. In this study, the critical role of the Musashi2-Numb axis in determining cell fate and relationship of the axis to impo...
Main Authors: | Foruzan Moradi, Sadegh Babashah, Majid Sadeghizadeh, Arsalan Jalili, Abbas Hajifathali, Elham Roshandel |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2019-06-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | http://ijbms.mums.ac.ir/article_12723_d9b444b5e7550b9883ddcd7802ad293e.pdf |
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