RNA-seq co-expression network analysis reveals anxiolytic behavior of mice with Efnb2 knockout in parvalbumin+ neurons

Abstract Anxiety disorders are the most common psychiatric disorders, and the change in the activity of the prefrontal cortex (PFC) is considered as the underlying pathological mechanism. Parvalbumin-expressing (PV+) inhibition contributes to the overall activity of the PFC. However, the molecular m...

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Bibliographic Details
Main Authors: Ying Sun, Le Ma, Jianhua Chen, Weidi Wang, Shiyu Peng, Ying Cheng, Yu Zhang, Jinghong Chen, Peijun Ju
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-021-00829-z