Carvacrol derivatives as mushroom tyrosinase inhibitors; synthesis, kinetics mechanism and molecular docking studies.

Carvacrol derivatives as mushroom tyrosinase inhibitors; synthesis, kinetics mechanism and molecular docking studies.

The present work describesthe development of highly potent mushroom tyrosinase inhibitor better than the standard kojic acid. Carvacrol derivatives 4a-f and 6a-d having substituted benzoic acid and cinnamic acidresidues were synthesized with the aim to possess potent tyrosinase inhibitory activity.T...

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Bibliographic Details
Main Authors: Zaman Ashraf, Muhammad Rafiq, Humaira Nadeem, Mubashir Hassan, Samina Afzal, Muhammad Waseem, Khurram Afzal, Jalifah Latip
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5441849?pdf=render

Internet

http://europepmc.org/articles/PMC5441849?pdf=render

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