Local computational methods to improve the interpretability and analysis of cryo-EM maps

Here, the authors present two local methods for analyzing cryo-EM maps: LocSpiral and LocBSharpen that enhance high-resolution features of cryoEM maps, while preventing map distortions. They also introduce LocBFactor and LocOccupancy, which allow obtaining local B-factors and electron density occupa...

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Bibliographic Details
Main Authors: Satinder Kaur, Josue Gomez-Blanco, Ahmad A. Z. Khalifa, Swathi Adinarayanan, Ruben Sanchez-Garcia, Daniel Wrapp, Jason S. McLellan, Khanh Huy Bui, Javier Vargas
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21509-5