Negative Regulation of Semaphorin-3A Expression in Peripheral Blood Mononuclear Cells Using MicroRNA-497-5p

Negative Regulation of Semaphorin-3A Expression in Peripheral Blood Mononuclear Cells Using MicroRNA-497-5p

Background: Semaphorin-3A (Sema3A), as a secreted semaphorin, is an immune modulator molecule participating in the pathogenesis of autoimmune diseases. MicroRNAs (miRNAs) modulate the target-gene expression at the post-transcriptional level. It has been proposed that miRNAs may be crucial to the mod...

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Bibliographic Details
Main Authors: Shima Shapoori, Mazdak Ganjalikhani-Hakemi, Mahsa Rezaeepoor, Fereshteh Alsahebfosoul, Sharifeh Khosravi, Masoud Etemadifar, Marjan Mansourian
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2019-07-01
Series:Iranian Journal of Medical Sciences
Subjects:
autoimmune disease
MicroRNAs
Mononuclear phagocyte system
Semaphorin-3A
Online Access:http://ijms.sums.ac.ir/article_44955_601b26541cf1caf899f855ce6d2e051c.pdf

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http://ijms.sums.ac.ir/article_44955_601b26541cf1caf899f855ce6d2e051c.pdf

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