Nonsaponin fraction of Korean Red Ginseng attenuates cytokine production via inhibition of TLR4 expression

Background: Ginsenosides of Korean Red Ginseng extracts (RGE) and its saponin components suppress secretion of inflammasome-mediating cytokines, whereas the nonsaponin fraction (NS) of RGE oppositely stimulates cytokine secretion. Although direct exposure of NS to macrophages in mice induces cytokin...

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Bibliographic Details
Main Authors: Huijeong Ahn, Byung-Cheol Han, Jeongeun Kim, Seung Goo Kang, Pyeung-Hyeun Kim, Kyoung Hwa Jang, Seung Ho So, Seung-Ho Lee, Geun-Shik Lee
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Journal of Ginseng Research
Online Access:http://www.sciencedirect.com/science/article/pii/S122684531730324X