Multi-parametric MRI at 14T for muscular dystrophy mice treated with AAV vector-mediated gene therapy.

The objective of this study was to investigate the efficacy of using quantitative magnetic resonance imaging (MRI) as a non-invasive tool for the monitoring of gene therapy for muscular dystrophy. The clinical investigations for this family of diseases often involve surgical biopsy which limits the...

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Bibliographic Details
Main Authors: Joshua Park, Jacqueline Wicki, Sue E Knoblaugh, Jeffrey S Chamberlain, Donghoon Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4391935?pdf=render