Validation of a Novel, Sensitive, and Specific Urine-Based Test for Recurrence Surveillance of Patients With Non-Muscle-Invasive Bladder Cancer in a Comprehensive Multicenter Study

Validation of a Novel, Sensitive, and Specific Urine-Based Test for Recurrence Surveillance of Patients With Non-Muscle-Invasive Bladder Cancer in a Comprehensive Multicenter Study

Bladder cancer (BC), the most frequent malignancy of the urinary system, is ranked the sixth most prevalent cancer worldwide. Of all newly diagnosed patients with BC, 70–75% will present disease confined to the mucosa or submucosa, the non-muscle-invasive BC (NMIBC) subtype. Of those, approximately...

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Main Authors: Rui Batista, João Vinagre, Hugo Prazeres, Cristina Sampaio, Pedro Peralta, Paulo Conceição, Amílcar Sismeiro, Ricardo Leão, Andreia Gomes, Frederico Furriel, Carlos Oliveira, João Nuno Torres, Pedro Eufrásio, Paulo Azinhais, Fábio Almeida, Edwin Romero Gonzalez, Bohdan Bidovanets, Thorsten Ecke, Pascal Stinjs, Álvaro Serrano Pascual, Rabehi Abdelmalek, Ainara Villafruela, Pastora Beardo-Villar, Nuno Fidalgo, Hakan Öztürk, Carmen Gonzalez-Enguita, Juan Monzo, Tomé Lopes, Mario Álvarez-Maestro, Patricia Parra Servan, Santiago Moreno Perez De La Cruz, Mario Pual Sanchez Perez, Valdemar Máximo, Paula Soares
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Genetics
Subjects:
non-muscle invasive bladder cancer
TERT promoter mutation
FGFR3 mutation
urinary test
Uromonitor®
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01237/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.01237/full

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