Uptake and tissue accretion of orally administered free carboxylic acid as compared to ethyl ester form of docosahexaenoic acid (DHA) in the rat.

AIM:The aim of this study was to compare the plasma exposure and tissue accretion of docosahexaenoic acid (DHA) in response to oral dosing of free carboxylic acid (OM3CA) and ethyl ester (OM3EE) forms. MATERIALS AND METHODS:Sixteen adult male Wistar rats, fed a low-fat, carbohydrate-rich, standard c...

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Bibliographic Details
Main Authors: Anna Lindblom, Cecilia Ericsson, Therese Hagstedt, Ann Kjellstedt, Jan Oscarsson, Nicholas D Oakes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6072001?pdf=render