Excessive biologic response to IFNβ is associated with poor treatment response in patients with multiple sclerosis.

Excessive biologic response to IFNβ is associated with poor treatment response in patients with multiple sclerosis.

Interferon-beta (IFNβ) is used to inhibit disease activity in multiple sclerosis (MS), but its mechanisms of action are incompletely understood, individual treatment response varies, and biological markers predicting response to treatment have yet to be identified.The relationship between the molecu...

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Bibliographic Details
Main Authors: Richard A Rudick, M R Sandhya Rani, Yaomin Xu, Jar-Chi Lee, Jie Na, Jennifer Shrock, Anupama Josyula, Elizabeth Fisher, Richard M Ransohoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3094352?pdf=render

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http://europepmc.org/articles/PMC3094352?pdf=render

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