CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents.

BACKGROUND: In the Western world, a major cause of blindness is age-related macular degeneration (AMD). Recent research in angiogenesis has furthered the understanding of choroidal neovascularization, which occurs in the "wet" form of AMD. In contrast, very little is known about the mechan...

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Main Authors: Marianne Houssier, William Raoul, Sophie Lavalette, Nicole Keller, Xavier Guillonneau, Barbara Baragatti, Laurent Jonet, Jean-Claude Jeanny, Francine Behar-Cohen, Flavio Coceani, Daniel Scherman, Pierre Lachapelle, Huy Ong, Sylvain Chemtob, Florian Sennlaub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2245984?pdf=render