Experimental Zika Virus Inoculation in a New World Monkey Model Reproduces Key Features of the Human Infection

Abstract A monkey model of Zika virus (ZIKV) infection is urgently needed to better understand transmission and pathogenesis, given its proven association with fetal brain defects in pregnant women and acute neurological illness. Here we experimentally infected 4 male marmosets with ZIKV (prototype...

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Bibliographic Details
Main Authors: Charles Y. Chiu, Claudia Sánchez-San Martín, Jerome Bouquet, Tony Li, Shigeo Yagi, Manasi Tamhankar, Vida L. Hodara, Laura M. Parodi, Sneha Somasekar, Guixia Yu, Luis D. Giavedoni, Suzette Tardif, Jean Patterson
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-17067-w