Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes.

Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes.

BACKGROUND: Monozygotic twins discordant for type 2 diabetes constitute an ideal model to study environmental contributions to type 2 diabetic traits. We aimed to examine whether global DNA methylation differences exist in major glucose metabolic tissues from these twins. METHODOLOGY/PRINCIPAL FINDI...

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Bibliographic Details
Main Authors: Rasmus Ribel-Madsen, Mario F Fraga, Stine Jacobsen, Jette Bork-Jensen, Ester Lara, Vincenzo Calvanese, Agustin F Fernandez, Martin Friedrichsen, Birgitte F Vind, Kurt Højlund, Henning Beck-Nielsen, Manel Esteller, Allan Vaag, Pernille Poulsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519577?pdf=render

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http://europepmc.org/articles/PMC3519577?pdf=render

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