ANTIFOLATES FOR CANCER CHEMOTHERAPY. PART I
In the review the structure of the basic antifolate antagonists, their intracellular enzyme targets, and their mechanisms of antitumor activity were considered. Folate antimetabolites, which were discovered in the last decade and trends in finding powerful inhibitors of folic acid metabolic pathways...
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| Format: | Article |
| Language: | English |
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Odessa I. I. Mechnikov National University
2014-11-01
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| Series: | Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ |
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| Online Access: | http://heraldchem.onu.edu.ua/article/view/31125 |