Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine

Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning Machine

In this study, we evaluated changes in focal adhesions (FAs) in two types of breast cancer cell (BCC) lines (differentiated MCF-7 and the triple-negative MDA-MB-231 cell line) exposed to simulated microgravity (s-μg) created by a random positioning machine (RPM) for 24 h. After exposure, the BCC cha...

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Bibliographic Details
Main Authors: Jayashree Sahana, Thomas J. Corydon, Markus Wehland, Marcus Krüger, Sascha Kopp, Daniela Melnik, Stefan Kahlert, Borna Relja, Manfred Infanger, Daniela Grimm
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
microgravity
breast cancer
multicellular spheroids
focal adhesions
cytoskeleton
extracellular matrix
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.672098/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.672098/full

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